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Vysnova Partners Acknowledged In Supporting Zika Global Health Program

vysnova-mentioned-cdc-article   Vysnova Partners Acknowledged In Supporting Zika Global Health Program

News update from Vysnova VEZ & ZEN program

Vysnova Partners was recently acknowledged in supporting the global health program on Zika research in Colombia by the U.S. Centers for Disease Control and Prevention (CDC) and the Colombia Instituto Nacional de Salud (INS). As an outcome of the joint international collaboration, CDC and INS recently published an article “Zika Virus Detection in Amniotic Fluid and Zika-Associated Birth Defects” in the American Journal of Obstetrics and Gynecology on January 15, 2020. This research was also supported by the Office of Infectious Disease, Bureau for Global Health, U.S. Agency for International Development (USAID), under the terms of an Interagency Agreement with CDC and funding by CDC. Vysnova Partners has contributed to this joint international collaboration by providing support for national surveillance efforts through a cooperative agreement (NU2GGH001732) under CDC. This is the recognition of the dedication of the VEZ & ZEN Program Management Office staff of Vysnova Partners across the U.S., Colombia, and Peru!

 

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Project Spotlight: Southeast Asia Biosurveillance and Epidemiology Research

The Problem:

The current global disease control strategy is focused almost entirely on responding to pandemics after they have emerged, leaving the global community vulnerable to rising human health threats. The emergence of Ebola and the Middle East Respiratory Syndrome serve as poignant examples. Considering the speed at which these types of infectious diseases can spread across the globe, the development of systems to prevent pandemics and to detect emerging threats early on is vitally important. In today’s world of global trade and air travel, the exponential rate through which pathogens can spread from one human to thousands across continents in a single day is of crucial concern, increasing the necessity for proactive and globally integrated pandemic response systems.

The Work:

NAMRU-2 is a leader in the U.S. Department of Defense’s disease surveillance efforts.  They are well-positioned to evaluate novel diagnostics products and therapeutic interventions, test disease control strategies, and to develop local expertise to detect and respond to emergent disease threats.

The Vysnova Impact:

As a contractor working with the U.S. Navy, Vysnova works to ensure full engagement of in-country collaborators and provides comprehensive program support to enhance biosurveillance and biosafety capacity building across study sites in Southeast Asia. The Vysnova team provides technical and managerial support to a plethora of cohort and surveillance studies across the Southeast Asia region in order to investigate and better understand vector-borne febrile and respiratory illnesses. Vysnova provides in-country staff to NAMRU-2 to assist in task completion tracking, develop and maintain data repositories, collaborate with local implementation partners and research institutes, and supply direct administrative and IT support to NAMRU-2. From our Washington, D.C.-based project office, Vysnova provides higher-level program-wide support by tracking study progress, overseeing contract compliance, and liaising with Principal Investigators to facilitate discussions on strategic directions of the research. Our collaborative and solution-based approach allows NAMRU-2 investigators to focus on the critical science at hand, developing strategies for combating future infectious disease threats to human health.

 

Zika Research in Infants and Pregnant Women in Colombia
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Project Spotlight: Zika Research in Infants and Pregnant Women in Colombia

The Problem:

Zika Virus (ZIKV) was declared a global health threat in 2016.  Although most of the cases can be attributed to infected bites of Aedes aegypti and Aedes albopictus mosquitoes, a proportion of new Zika infections are due to sexual transmission from infected males to their partnersZIKV infection features general symptoms such as mild headaches and fever.  However, consequences of infections during pregnancy can be catastrophic. ZIKV infections during pregnancy are causally linked to microcephaly in new born babies (small heads) and other negative pregnancy outcomes.

Learn more about Zika from the CDC.

The Work:

The project Zika en Embarazadas y Ninos (ZEN) targets the population who were exposed to ZIKV.  ZEN has been executed in two phases.   During the first phase, the project staff followed a cohort of pregnant women, their partners, and their newborn infants, in the regions of Atlántico, Valle, and Santander in Colombia to better understand the association between ZIKV during pregnancy and the spectrum of possible adverse outcomes related to infection during pregnancy.  During the second phase, the babies from the first phase-cohort are followed to further explore functional deficits, their magnitude, and their association to other deficits later in life.  For this purpose, the Centers of Disease Control and Prevention and the Instituto Nacional de Salud in Colombia proposed the recruitment and follow-up of 5000 women and their 1250 children, until children reach 4 years of age.

The Vysnova Impact:

Vysnova provides comprehensive project management support for the scientific research of the ZEN study. We help our client meet their objectives by managing international purchases, human resources, technical requirements, and logistics, all while controlling costs and providing risk management.

Through crucial partnerships and subcontractors, Vysnova ensures high quality research and procures the technical skills needed for the study. We partner with academic institutions conducting similar research in Latin America to increase the study’s sample size of women who have or have been exposed to ZIKV. Vysnova also works closely with local companies to provide digital data storage and management for the samples collected from the field. This allows our client to easily analyze and access the data, which will be utilized for years to come. Vysnova also recruits and hires technical experts in child psychology that train field staff to assess babies with specific tools. These assessments analyze motor skills, psychological capacity, and other developmental patterns found within the children being studied. These skills are easily transferable to other ZIKV studies and enhance specialization of Colombian medical staff that will be used long after the study concludes.

The success of our clients’ projects is at the forefront of our efforts here at Vysnova. Our greatest contribution to that success lies in the relationships that Vysnova fosters through partnerships, subcontractors, local staff, vendors, and consultants. Vysnova looks forward to continuing to support public health projects within Latin America and globally.

Vysnova Partners Inc. Awarded TO 0738 Under NAMRU-2 SABER II IDIQ Contract
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Vysnova Partners Inc. Awarded TO 0738 Under NAMRU-2 SABER II IDIQ Contract

Vysnova Partners Inc. Awarded TO 0738 Under NAMRU-2 SABER II IDIQ Contract

Vysnova Partners Inc. Awarded TO 0738 Under NAMRU-2 SABER II IDIQ Contract

September 30, 2018:  Vysnova Partners Inc. (Vysnova) has been awarded Task Order N6264518F0738 (TO 0738) under the Navy Medical Unit 2 (NAMRU 2) Southeast Asia Biosurveillance and Epidemiology Research (SABER) II indefinite-delivery/indefinite-quantity (IDIQ) contract. Under TO 0738 Vysnova will provide an in-depth analysis for a clinical study evaluating the role of the candidate predictive biomarker, tryptase, for dengue fever security.

Vysnova Supports Enhancing Civilian-Military Cooperation
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Vysnova Supports Enhancing Civilian-Military Cooperation to Accelerate Malaria Elimination in Southeast Asia

The Heads of State from the Association of Southeast Asian Nations (ASEAN) member nations stated their commitment to an “Asia Pacific free of Malaria by 2030” at the 9th East Asia Summit – which was sponsored by Vysnova Partners. This mandate for a malaria-free Asia Pacific creates an unprecedented opportunity to strengthen ties between civilian and military health systems and regional militaries.

On June 26-28, 2017, the Armed Forces Research Institute of Medical Science (AFRIMS) organized a meeting titled: “Enhancing Civilian-Military Cooperation to Accelerate Malaria Elimination in Southeast Asia” in Bangkok, Thailand. The meeting brought together the Ministry of Defense (MoD) and Ministry of Health (MoH) malaria officials from Myanmar, Thailand, Cambodia, Laos, Indonesia, Vietnam, Australia and the United States.

Vysnova’s Dr. Sara Canavati was actively involved in the MoH and MoD delegations from Vietnam. During the event, Dr. Canavati facilitated group discussions and found items in which the MoH and MoD could work together on malaria elimination activities, including surveillance, case management and advocacy.

Since malaria is a common problem in the military, and since malaria does not know borders, regional collaborations involving all affected populations are important to achieve malaria elimination. The meeting was instrumental for reviewing existing military and civilian national malaria collaborations, identifying and prioritizing key areas of mutual military-civilian interest and discussing ways in which regional militaries can assist national malaria elimination goals.

Three action points on how the civilian and military sectors can more effectively collaborate to achieve elimination in four areas of mutual interest (Case Detection and Management and Disease Prevention; Surveillance, Monitoring and Evaluation; Operational Research/Training and Advocacy) were identified and documented by meeting attendees through a breakout team format.

Advocacy for malaria elimination was the theme that military attendees found most challenging due to the hierarchical structure of the military. Among several presentations, East Africa Malaria Task Force and Experiences from African Military Medical Departments were shared to serve as an example of military-advocacy.

Financing was another key barrier identified. The chair of the regional steering committee (RSC) for the Global Fund, Prof Arjen Dondorp and The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFTAM) Geneva assured their support and commitment to finance military operations for malaria elimination in South East Asia. This was a historical achievement as this will be the first time ever the GFTAM finances the military for malaria elimination.

One significant outcome of the meeting is that the military will now be represented in the RSC for the Global Fund “Regional Artemisinin-resistance Initiative 2 Elimination (RAI2E)” malaria grant.

Vysnova’s Dr. Sara Canavati with officials from MoD and MoH from Myanmar, Thailand and Vietnam at a visit of the Phayathai Palace in Bangkok after an intensive meeting at AFRIMS.

Vysnova’s Dr. Sara Canavati with officials from MoD and MoH from Myanmar, Thailand and Vietnam at a visit of the Phayathai Palace in Bangkok after an intensive meeting at AFRIMS.